Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Retinoids in Mammalian Reproduction, with an Initial Scoping Effort to Identify Regulatory Methods
Responsible organisation
2020 (English)Book (Other academic)
Abstract [en]

This Nordic report builds on ideas brought forward in the OECD Detailed Review Paper (DRP) 178 on screening and testing methods and endpoints for evaluating endocrine disruptors. It was identified that the retinoid system is not presently included in any OECD test guideline, and that it is urgent to cover this knowledge gap.

The present TemaNord report is a contribution to an upcoming OECD DRP on retinoids. An overview of retinoid biology in female and male reproduction is presented. The report identifies that, in general, there is a lack of studies investigating effects of chemicals on reproduction, while simultaneously examining effects on retinoid related parameters. This is a major data gap. However, selected in vitro and/or in silico retinoid-related endpoints, presented in this report, could possibly be part of a broader screening test battery aimed at reproductive toxicity.

Place, publisher, year, edition, pages
Copenhagen: Nordisk Ministerråd, 2020. , p. 116
Series
TemaNord, ISSN 0908-6692 ; 2020:507
National Category
Environmental Management
Research subject
Environment and Climate; Chemicals
Identifiers
URN: urn:nbn:se:norden:org:diva-5932DOI: 10.6027/temanord2020-507ISBN: 978-92-893-6530-7 (electronic)ISBN: 978-92-893-6531-4 (electronic)OAI: oai:DiVA.org:norden-5932DiVA, id: diva2:1424722
Available from: 2020-04-19 Created: 2020-04-19 Last updated: 2020-04-19

Open Access in DiVA

Download free PDF(4581 kB)136 downloads
File information
File name FULLTEXT01.pdfFile size 4581 kBChecksum SHA-512
ce56e2b811174375ea2a0221e246e23d5671524721e89cae660e00358da77ad964b07c19bf817e47e810fa5f8c32fb3873bcb442374966510a83ad7083d1d5d6
Type fulltextMimetype application/pdf

Other links

Publisher's full textOnline publication
Environmental Management

Search outside of DiVA

GoogleGoogle Scholar
Total: 136 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
isbn
urn-nbn

Altmetric score

doi
isbn
urn-nbn
Total: 273 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf