The possibility to use enzymes as oxygen scavengers embedded in latex/ TiO2 dispersion coatings was demonstrated in a series of experiment where different grades of paperboard were coated. Simple draw-down coatings were used as application method. The enzyme system consisted of glucose oxidase in combination with an enzyme that removes peroxides (peroxidase/catalase). Glucose or glucose derivatives were used as substrates for the enzymatic reaction. The enzyme-containing coatings seemed to persist drying at elevated temperatures for limited period of times. The period of time with no dramatic decrease in enzyme activity was substantial shorter than drying times in real industrial coating and printing processes (on condition that the web will be cooled down before reeling up). The coatings could also be stored in air at room temperature for long period of times without any loss in enzyme activity.