Per- and polyfluoroalkyl substances (PFAS) are a large group of substances that have been widely used for decades due to their surface-active properties. However, their characteristic resistance to degradation in combination with other properties of concern for human health and the environment has resulted in regulatory actions such as restrictions towards this group of substances, in the EU and globally. Compliance with restrictions as well as enforcement by authorities is key to reduce intentional use of restricted PFAS in articles and chemical products. To analyse PFAS accurately, robust and reliable analytical methods are required. This report evaluates the current situation related to PFAS-analyses and enforcement (including challenges and needs) and propose measures/strategies to enable and/or improve enforcement of, and compliance with current and future, PFAS restrictions.