This policy brief aims to shed some light on the mission's approach, specifically within innovation policy, and how it is interpreted and implemented at different territorial levels. First, the academic debate around the territorial dimensions of MOIPs is presented, followed by a brief discussion of how MOIPs have been adopted so far at the supra-national, national and sub-national levels. More specifically, a snapshot of the innovation policy landscape and the degree of penetration of mission and transformative approaches in Denmark, Finland and Sweden is presented. Furthermore, the interpretation and adoption of missions at the regional level are discussed based on the results of three Nordic case studies, including Northern Jutland (DK), Ostrobothnia (FI) and Västerbotten (SE). The final section discusses the implications of adopting MOIPs and provides a list of recommendations for Nordic regions.